Analysis of CDC Data on COVID-19 Case Fatality Rate in Winter 2021-22 by Vaccination Status and Age
How did vaccines and boosters impact Coronavirus lethality rates in US in Winter 2021-22?
Fig. 1. CFR for all ages by month, vaccine product and status. The Pfizer vaccine has a greater CFR for people boosted than only with the original two doses, once boosted the best vaccine to reduce death probability is Jannsen.
Fig. 2. CFR for 12-17 Age Group, there were no recorded fatalities for the boosted.
Fig. 4. CFR for 50-64 Age Group.
Graphically in Figs. 1 to 5 there is an appreciable reduction in lethality for the vaccinated people and more for the boosted people with respect to the unvaccinated group (this analysis would be even more telling if there were data for people who had been previously infected, so as to compare vaccine effectiveness against the natural immunity).We calculated the relative change in CFR for each group to put a number on the observations, and also performed a t-test to determine if the difference between CFR is statistically significant.
Table with the summary of results:
____________________________________________________________________________________________ t-Test on CFR by Vax. Status per Age Range in Winter 21-22: 12-17 18-49 50-64 65+ CFR Unvaxxed (%) 0.0062 0.09501 0.962456 5.779413 CFR Vaxxed (%) 0.003122 0.027892 0.321796 3.349548 CFR Boosted (%) 0.0 0.01347 0.1576 1.42223 CFR Reduction Vax-Unvax (%) 49.648033 70.642958 66.565154 42.043468 CFR Reduction Boosted-Unvax (%) 100.0 85.82297 83.625256 75.391441 p-value Vax-Unvax 0.429324 0.047613 0.056727 0.037261 Significant Vax-Unvax No Yes No Yes p-value Vax-Boosted 0.258723 0.259471 0.20088 0.004133 Significant Vax-Boosted No No No Yes Analysis: https://cadecastro.com Source: https://data.cdc.gov/api/views/d6p8-wqjm/rows.csv ____________________________________________________________________________________________
Analysis Code:GitHub Repository: https://github.com/cadecastro/covid19/blob/main/cdc_cases_deaths_vax_boost_age.py